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. 2014 Jul 3;5:240–244. doi: 10.1016/j.nicl.2014.06.007

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© 2014 The Authors. Published by Elsevier Inc. All rights reserved.

This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Fig. 1 — A) (T) Map of the Parkinson's disease (PD)-related metabolic brain patterns by using 17 healthy controls (HC) and 19 PD (PD) patients (PDRPmCT_17HC19PD). The map was overlaid on a T1 MR template. Relative metabolic decreases (blue) and increases (red) compared to the control group are thresholded at T = 3.7–6.7 (p = 0.001). Seven transversal slices through the brain are shown.B) (T) Maps of the PD-related metabolic and perfusion covariance brain patterns (PDRP-mCT_17HC14PD and PDRP-PCASL_17HC14PD) calculated by using the same HC and PD subjects and overlaid on a T1 MR template. Relative metabolic and perfusion decreases (blue) and increases (red) compared to the control group are thresholded at T = 2.5–5.0 (p = 0.02). Seven transversal slices through the brain are shown.C) Example of the mean PCASL images of all healthy controls. Seven transversal slices through the brain are shown. Yellow/red = high perfusion, black/blue = low perfusion.