Table 2.
Characteristics of patients in the group who developed radiation related pulmonary complications versus the group of patients who did not develop such complications
| No RT Pulmonary Complications (n=32) | RT Pulmonary Complications (n=18) | Total Study Population (n=50) | |
|---|---|---|---|
| Mean age (yr) | 67.2 | 68.4 | 67.6 |
| Sex (M:F) | 16:16 | 10:8 | 26:24 |
| Tumor stage | |||
| I | 8 (25%) | 6 (33.3%) | 14 |
| II | 1 (3.1%) | 0 (0.0%) | 1 |
| III | 11 (34.4%) | 9 (50.0%) | 20 |
| IV | 5 (15.6%) | 0 (0.0%) | 5 |
| Recurrence | 7 (21.9%) | 3 (16.7%) | 10 |
| RT Technique | |||
| Streotactic | 11 (34.4%) | 6 (33.3%) | 17 |
| IMRT* | 17 (53.1%) | 9 (50.0%) | 26 |
| 3D-Conformal | 3 (9.4%) | 2 (11.1%) | 5 |
| Proton Therapy | 1 (3.1%) | 1 (5.6%) | 2 |
| Mean Total RT dose (Gy) | 56.8±9.9 | 55.1±11.4 | 56.1±10.4 |
| Mean Lung Dose (Gy) | 15.0±8.1 | 15.9±7.5 | 15.5±7.6 |
| V20 (%) ** | 26.5±13.3 | 27.7±13.5 | 26.9±13.4 |
| Prior RT | 3 (9.4%) | 5 (27.8%) | 8 |
| Prior Surgical Resection | 3 (9.4%) | 2 (11.1%) | 5 |
| Prior COPD | 9 (28%) | 6 (33%) | 15 |
| Chemotherapy | 25 (78.1%) | 9 (50%) | 34 |
*
IMRT=Intensity Modulated Radiation Therapy,
**
V20= Percent lung volume irradiated with >20Gy.