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. 2014 Jul 25;21:34. doi: 10.1051/parasite/2014037

Table 1.

Results for ELISA tests rEm18 and Em2-Em18, and rEm18-ICT for AE (alveolar echinococcosis), CE and PE (cystic and polycystic echinococcosis), and other pathologies. Percentages of sensitivity, specificity, and the performance index for each test are shown.

No. of seropositive samples for the three tests
No. of samples rEm18-ICT rEm18-ELISA Em2-Em18-ELISA
AE 30 27 26 29
CE/PE 16 5 4 5
Other 66 1 3 5
Sensitivity, % 90.0 86.7 96.7
(95% CI) (78.4–96.1) (74.4–93.9) (85.8–99.4)
Specificity, % 92.7 91.5 87.8
(95% CI) (88.4–94.9) (87.0–94.1) (83.8–88.8)
Youden index 0.83 0.78 0.85
(95% CI) (0.67–0.91) (0.61–0.88) (0.70–0.88)
Accuracy, % 92.0 90.2 90.2
(95% CI) (85.7–95.2) (83.6–94.1) (84.4–91.6)
Positive likelihood ratio (LR+) 12.3 10.2 7.9
(95% CI) (6.7–18.9) (5.7–16.0) (5.3–8.9)
Negative likelihood ratio (LR−) 0.11 0.15 0.04
(95% CI) (0.04–0.25) (0.06–0.30) (0.01–0.17)
Diagnostic odds ratio 114.0 69.6 208.8
(95% CI) (27.7–461.2) (19.4–248.5) (31.5–1314.4)