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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Future Med Chem. 2014 Mar;6(4):413–427. doi: 10.4155/fmc.14.10

Figure 2. Fragments targeting Class A β-lactamase.

Figure 2

(A) Anionic fragments identified by virtual screening against CTX-M Class A β-lactamase [61]. Many of these fragments also demonstrated activity against the Class C enzyme AmpC. (B) x-ray crystallographic structures of fragments in complex with CTX-M β-lactamase.