Table 3.

Regression models assessing the effect of chronic pain (CP) on hippocampal subfield volumes.

Hippocampal subfield		Models for CP in Total Sample*			Models for CP in Women**			CP Models for CP in Men**
		Beta	t	p-value	Beta	t	p-value	Beta	t	p-value
CA1	Left	0.03	0.28	0.773	−0.01	−0.10	0.917	−0.02	−0.11	0.910
	Right	−0.13	−1.26	0.211	−0.24	−1.86	0.069	−0.04	−0.18	0.858
CA2/CA3	Left	−0.12	−1.09	0.276	−0.26	−1.98	0.053	0.08	0.37	0.709
	Right	−0.20	−1.94	0.055	−0.34	−2.65	0.011	0.02	0.13	0.895
CA4/DG	Left	−0.08	−0.82	0.415	−0.26	−1.95	0.057	0.13	0.65	0.519
	Right	−0.17	−1.66	0.101	−0.34	−2.66	0.010	0.07	0.34	0.731
Pre-subiculum	Left	−0.13	−1.31	0.193	−0.28	−2.19	0.033	0.19	1.01	0.321
	Right	−0.07	−0.65	0.515	−0.14	−1.03	0.307	0.18	0.93	0.360
Subiculum	Left	−0.04	−0.44	0.656	−0.26	−1.95	0.056	0.29	1.43	0.164
	Right	−0.09	−0.82	0.409	−0.18	−1.39	0.169	0.07	0.34	0.735
Fimbria	Left	−0.10	−0.95	0.341	−0.30	−2.33	0.023	0.26	1.26	0.216
	Right	0.02	0.25	0.799	−0.02	−0.13	0.892	0.03	0.163	0.872
Hippocampal Fissure	Left	0.04	0.39	0.695	−0.08	−0.58	0.561	0.16	0.786	0.439
	Right	−0.04	−0.35	0.726	−0.08	−0.67	0.505	0.01	0.048	0.962

^*Models include age, gender, education, and eTICV as covariates.

^**Models include age, education, and eTICV as covariates

^•eTICV= estimated Total Intracranial Volume, HV=Hippocampal volume