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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Obstet Gynecol. 2014 Jul;124(1):83–90. doi: 10.1097/AOG.0000000000000336

Table 2.

Frequency of All Other-Than-Common Benign Copy Number Variants Associated With Ultrasonographically Detected Abnormalities

Anomaly System N=752 CNV Array Findings (n) % CNV (95% CI) P*
All anomalies
 Isolated 498 28 5.6% (3.6 – 7.7) 0.041
 Multiple 254 33 13.0% (8.9 – 17.1) <0.001
Excluding neck anomalies
 Isolated 312 21 6.7% (4.0 – 9.5) 0.009
 Multiple 206 28 13.6% (8.9 – 18.3) <0.001
*

Compared to frequency of CNV among women with advanced maternal age and no fetal anomalies (n = 71/1966, 3.6%).

CNV, copy number variant; CI, confidence interval.