Figure 2.
a) (Z)-1-{N-methyl-N-[6-(N-methylammoniohexyl)amino]diazen-1-ium-1,2-diolate (MAHMA/N2O2); b) diazeniumdiolated diamine cross-linked silicone rubber (DACA-6/N2O2-SR). Note the similarity in the NO donor to MAHMA/N2O2. However upon NO release, the diamine remains in the polymer backbone; c) dibutylhexanediamine diazeniumdiolate (DBHD/N2O2). Note the similarity in the NO donor to MAHMA/N2O2. However the methyl group substituents are replaced with butyl groups making DBHD/N2O2 more lipophilic. Reproduced and adapted with permission.[115] Copyright 2003, Elsevier.