Table 2.
Protein and Select Gene Expression in Active Healthy and Inactive Frail Older Women
| Active | Inactive | |
|---|---|---|
| Protein expression | ||
| Foxo3a (Ser253) | 1.50±0.39 | 2.61±0.41 |
| AMPKα (Thr172) | 1.55±0.25 | 2.37±0.27* |
| AMPKα | 2.57±0.40 | 3.22±0.47 |
| Beclin1 (Ser93/96) | 3.07±0.48 | 4.03±0.40 |
| Beclin1 | 4.32±0.63 | 3.84±0.48 |
| VPS34 | 1.96±0.18 | 1.88±0.23 |
| Gene expression | ||
| FOXO3A | 1.05±0.15 | 0.50±0.10* |
| MUL1 | 1.01±0.07 | 0.83±0.08 |
| MAFBX | 1.07±0.15 | 0.58±0.07* |
| MURF1 | 1.08±0.16 | 0.59±0.08* |
| NEDD4-1 | 1.03±0.10 | 0.66±0.09* |
Notes: AMPKα = AMP-activated protein kinase alpha. Data are mean ± SE. *Indicates significantly different from active healthy older women (p < .05).