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DNMT1 and DNMT3a mRNA expressions are higher in Ames dwarf mice at 3 months of age. Liver DNMT mRNA expression is shown for wild-type (open bars) and dwarf mice (gray bars) at 3, 12, and 24 months of age (n = 7–8). Mean relative changes in expression are shown ± SEM. ***p < .001.
