Table 5. Effect of complement receptor blocking on the presentation of major histocompatibility complex class II molecules and the expression of co-stimulatory molecules on monocytes infected with the dengue virus.
Co-expression | No blocking | Blocking with anti-CD35 | Blocking with anti-CD11b |
% monocytes infected | % monocytes infected | % monocytes infected | |
CR1 (CD35)+CD86+, median (range) | 3.2 (1.9–6.2) | 2.0 (1.3–3.5) | 6.3 (2.8–7.6) |
CR3 (CD11b)+CD86+, median (range) | 19.6 (11.4–43.0) | 26.8 (18.6–59.3) | 23.6 (14.4–44.3) |
CR4 (CD11c)+CD86+, median (range) | 13.2 (10.8–30.0) | 13.4 (9.8–34.6) | 13.9 (12.6–23.0) |
CD59+HLA-DR+, median (range) | 85.7 (67.2–93.2) | 89.2 (63.9–97.3) | 89.9 (66.7–95.0) |
CD59+CD40+, median (range) | 5.0 (4.2–17.0) | 5.3 (1.4–8.9) | 4.4 (3.4–9.1) |