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Amino acid sequences of FDH from yeast: CbFDH; FDH from fungi: CsFDH; FDHs from bacteria: AaFDH, MsFDH, PsFDH, and TsFDH. The blue background indicates the additional sequence regions for the N- and C-terminal loops of bacterial FDHs. Conservative amino acids are represented in red box and secondary structure elements are assigned according to the structure of CbFDH (pdb code: 2FSS).
