Figure 1. SNV concordance between tools for one read set (Sample 2).

a) Number of variants in dbSNP (v137) plotted against number of variants called at various levels of depth. Depth begins on far right at 6 bp and each point represents increasing depth of 1 bp coverage. b) Overlap of known SNVs called c) Overlap of known non-synonymous SNVs called d) Overlap of SNVs called in COSMIC. All SNP calls were assessed at depth of 6. *BWA-MEM.