Fig. 6.
Postmortem histology of tumors after intravenous delivery of either pCMV-TK (a, c, d) or pEGFP-C1 (b)-loaded microbubbles and treatment with ultrasound and GCV. (a, b) Acellular zones (arrows) visible under H&E stain. (c) Merged image of two sister slides, one stained by Heoscht 33342 (blue overlay) and one stained by H&E. (d) Variable vWF staining in acellular zones (arrows).