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. 2014 Jul 25;9(7):e102731. doi: 10.1371/journal.pone.0102731

Table 1. The differential protein spots between control and DKA-exposed treatments by MALDI-TOF-MS.

Spot# Accession NO. Gene product MW(kDa) pI Matched Peptides Cov Score E-value Fold change (Mean ± SD) Location chromosome
2416 gi|57222259 Talin-1 272579 5.86 28 14% 68 0.006 −2.19±0.46 10
2411 gi|45387723 Uncharacterized protein LOC402952 37349 9.23 7 36% 58 0.055 −3.64±0.05 21
2327 gi|41944596 Heat shock protein 4 95585 5.10 17 24% 63 0.020 −2.34±0.71 14
6459 gi|326666090 Multidrug resistance-associated protein 1-like 228609 8.71 15 10% 64 0.014 −3.53±0.39 3
4407 gi|366039974 ATP synthase subunit beta, mitochondrial 55210 5.14 12 30% 76 0.001 −3.51±0.05 11
3502 gi|82181062 Beta-coat protein 108047 5.72 17 24% 62 0.023 −3.72±0.43 7
3730 gi|300680985 EF-hand calcium-binding domain-containing protein 4A 46004 5.82 18 39% 63 0.018 −3.15±0.56 25
1325 gi|18859049 Myosin light chain, phosphorylatable, fast skeletal muscle a 18967 4.68 11 72% 90 4.1e-05 −2.70±0.06 3
2203 gi|62202893 Mcm10 protein, partial 37666 5.48 11 32% 66 0.009 −3.40±0.56 4
2350 gi|18858249 Actin, alpha cardiac muscle 1 42288 5.23 12 43% 59 0.048 −6.95±0.22 17
7301 gi|42560193 Actin, cytoplasmic 1, N-terminally processed 42068 5.30 8 27% 66 0.009 −4.27±0.38 1
7309 gi|55925421 Uncharacterized protein LOC492776 27126 5.46 11 45% 63 0.019 −2.23±0.30 9
1561 gi|125838841 Acid sphingomyelinase-like phosphodiesterase 3b-like 52763 6.73 10 21% 67 0.008 3.76±0.33 16
1448 gi|353558878 Maternal embryonic leucine zipper kinase 77612 8.88 7 18% 59 0.050 3.77±0.05 1
3319 gi|28277651 Actin, alpha 1, skeletal muscle 42298 5.23 15 47% 72 0.003 5.02±0.13 17
4359 gi|313482836 Plasma membrane calcium ATPase 3a 130715 5.41 15 14% 69 0.005 2.10±0.40 8
5339 gi|161612176 LOC560422 protein, partial 34141 8.56 9 32% 58 0.062 5.98±0.32 2
5346 gi|292619409 Hypothetical protein LOC794259 291570 6.76 22 11% 61 0.031 5.27±0.41 12
2359 gi|62955473 Actin, gamma-enteric smooth muscle 42232 5.29 12 34% 74 0.002 6.85±0.09 1
0297 gi|61806478 Cyclin-H 37420 5.77 13 40% 71 0.003 5.72±0.36 5
02105 gi|120538416 LOC557463 protein, partial 42884 8.73 10 36% 73 0.002 3.79±0.61 13
3225 gi|161611678 Zgc:171522 protein 22889 9.04 9 38% 64 0.016 4.73±0.23 1
4228 gi|68398755 Megakaryocyte-associated tyrosine-protein kinase 50794 8.98 13 20% 61 0.033 2.53±0.06 22
2258 gi|41053317 Developmentally-regulated GTP-binding protein 1 40726 8.83 9 21% 65 0.013 4.44±0.64 10
8411 gi|68353786 Hypothetical protein LOC558776 54015 9.60 8 28% 63 0.019 2.50±0.25 1
7648 gi|326674120 Vacuolar protein sorting-associated protein 37B-like 34412 9.62 6 20% 62 0.026 3.18±0.42 15

Note: In “fold change” column, “+” indicates up-regulation, and “−” denotes down-regulation, respectively.