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. Author manuscript; available in PMC: 2014 Jul 25.
Published in final edited form as: Bioorg Med Chem. 2012 Jul 3;20(17):5269–5276. doi: 10.1016/j.bmc.2012.06.042

Figure 2.

Figure 2

Compound 2 and mechano-allodynia in rats. Withdrawal threshold to von Frey filaments was measured 2 h after a subcutaneous injection of 1 (C1) or 2 (C2) in rats with sciatic nerve ligation and mechano-allodynia. N = 5 rats per group. Data represent the mean and SEM; 1-way ANOVA with Tukey’s post-hoc tests. C1; compound 1, C2; compound 2. Drug dose is in mg of drug per kg body weight of rat. *p <0.05, **p <0.01, ***p <0.001.