Figure 4. In-vivo replication studies of base J and 5hmU in HEK293T cells.

(A) Experimental procedures for determining the effects of 5hmU and base J on DNA replication in cells. (B) Representative PAGE gel image showing the restriction fragments. (C) The bypass efficiencies of base J and 5hmU in HEK293T cells. The data represent the mean and standard deviation of results from three independent replication experiments.