Table 2. Pathways implicated during neuronal maturation.
DESCRIPTION | p-value | GENES |
Proliferation and differentiation related pathways | 0.005 | Abl1 , Araf, Axin2 , Brca2, Cdh1, Ctnna2, E2f2 , Fgf12, Fgfr1 , Gli2, Igf1r , Ikbkb , Ikbkg, Itgb1 , Kit , Pax8, Plcg1, Prkcb , Ptch1, Ptgs2 , Pik3cd, Ralgds , Tcf7l1, Wnt11 |
Cell adhesion molecules | 0.02 | Cd40, Cd8b1, Cdh1, Cdh4 , Cntn1 , F11r , H2-d1, Itgb1 , Madcam1, Ncam1 , Negr1 , Nrxn1 , Nrxn3 |
Neurotrophin signalling pathway | 0.015 | Abl1 , Calm1, Camk2d , Ikbkb , Ntrk2 , Pik3cd, Plcg1, Rapgef1 , Sh2b1, Sh2b3 , Sort1 , Trp73 |
Prostate cancer | 0.01 | Araf, Creb3l2, E2f2, Fgfr1, Igf1r, Ikbkb, Ikbkg, Pdgfc, Pik3cd, Tcf7l1 |
Glioma | 0.013 | Araf, Calm1, Camk2d, E2f2, Igf1r, Pik3cd, Plcg1, Prkcb |
Genes identified had differentially expressed mRNAs and lncRNAs associated with them. mRNA of genes in bold were predicted to be targets of the altered miRNAs as shown in Table S4.