Table 5.
Clinical characterization of autistic individuals, whose mothers carry either the 37, 39 or 73 kDa antibrain antibodies (mAb+). Only continuous variables reaching a nominal P < 0.05 are listed. Data are reported as N (%).
Maternal antibody | Continuous variables | mAb+
|
mAb−
|
P | ||
---|---|---|---|---|---|---|
N | Mean ± SD | N | Mean ± SD | |||
37 kDa | VABS Adaptive behavior composite | 13 | 50.9 ± 15.8 | 106 | 71.8 ±24.4 | 0.008 |
Numbers of brothers | 18 | 1.1 ±1.0 | 264 | 0.5 ± 0.6 | 0.012 | |
Age at verbal language development (mo) | 19 | 29.6 ± 24.2 | 244 | 17.0 ±14.4 | 0.020 | |
39 kDa | ADOS language/communication | 31 | 5.3 ± 2.7 | 85 | 6.5 ± 3.0 | 0.020 |
ADOS social interaction | 31 | 9.4 ± 3.0 | 85 | 10.6 ±3.1 | 0.041 | |
73 kDa | Principal component 3 “neurodevelopmental delay” | 28 | 0.37 ± 0.9 | 102 | −0.17 ±0.9 | 0.009 |