Table 6.
Clinical characterization of autistic individuals, whose mothers carry both the 39 and 73 kDa antibrain antibodies (mAb+/+), as compared to children whose mothers carry either mAb (+/−) or none (−/−). Only (A) categorical and (B) continuous variables reaching a nominal P < 0.05 are listed. Data are reported as N (%).
| N | Ab+/+ | Ab+/− | Ab−/− | P | ||
|---|---|---|---|---|---|---|
|
| ||||||
| (A) Categorical variables | ||||||
| Epilepsy | Absent | 284 | 12 (85.7) | 81 (95.3) | 178 (96.2) | 0.013 |
| Rare | 0 (0.0) | 4 (4.7) | 3 (1.6) | |||
| Frequent | 2 (14.3) | 0 (0.0) | 4 (2.2) | |||
| Verbal language | Typical development | 267 | 2 (16.7) | 22 (26.4) | 58 (33.9) | 0.015 |
| Delayed | 4 (33.3) | 39 (46.4) | 75 (43.9) | |||
| Regression | 2 (16.7) | 5 (6.0) | 1 (0.6) | |||
| Never Acquired | 4 (33.3) | 18 (21.4) | 37 (21.6) | |||
| Sleep/wake cycle | Normal | 232 | 3 (30.0) | 42 (57.5) | 100 (67.1) | 0.036 |
| Abnormal | 7 (70.0) | 31 (42.5) | 49 (32.9) | |||
| I.Q. | >70 | 180 | 2 (22.2) | 24 (43.6) | 29 (25.0) | 0.040 |
| ≤70 | 7 (77.8) | 31 (56.4) | 87 (75.0) | |||
| Ab+/+ | Ab+/+ | Ab−/− | P | ||||
|
|
|
|
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| N | Mean ± SD | N | Mean ± SD | N | Mean ± SD | ||
|
| |||||||
| (B) Continuous variables VABS (motor skills) | 6 | 69.3 ± 18.0 | 34 | 92.1 ± 24.5 | 72 | 84.5 ± 23.7 | 0.046 |