Table 1.
Baseline Population Characteristics
| Testing Cohort | Replication Cohort | |
|---|---|---|
| Number of participants | 545 | 502 |
| Age (y), mean (SD) | 41.3 (8.2) | 41.1 (7.8) |
| Age range (y) | 23.1–70.1 | 23.4–65.4 |
| FEV1% predicted, mean (SD) | 97.93 (12.30) | 96.72 (11.00) |
| FEV1 (L), mean (SD) | 3.96 (0.59) | 3.95 (0.56) |
| FVC %predicted, mean (SD) | 97.35 (10.98) | 96.45 (10.39) |
| FVC (L), mean (SD) | 4.97 (0.71) | 4.96 (0.70) |
| FEV1/FVC, mean (SD) | 0.80 (0.06) | 0.80 (0.58) |
| FEV1/FVC %predicted, mean (SD) | 100.54 (7.14) | 100.49 (7.37) |
| Smoking status (%) | ||
| Nonsmoker | 37.2 | 31.0 |
| Current smoker | 30.4 | 35.5 |
| Former smoker | 32.3 | 33.5 |
| Number of follow-up visits (N), mean (SD) | 7.4 (2.3) | 7.7 (2.2) |
| Number of years of follow-up (y), mean (SD) | 24.64 (6.70) | 25.42 (6.20) |
Notes: FEV1 = forced expiratory volume in 1 s; FVC = forced vital capacity.