Table 3. Kappa correlation of patients classified by the 21 gene mutational signature with therapy resistance. Values in the contingency table represents the number of unique sample IDs corresponding to the row and column labels.

	Progressive disease	Complete response, partial response, or stable disease	Total
high-risk	8	42	50
low-risk	18	190	208
Total	26	232	258
Kappa	0.08984
P value (one-sided, right-tailed)	0.06065