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. 2014 Apr 14;13(11):1798–1810. doi: 10.4161/cc.28757

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Copyright © 2014 Landes Bioscience

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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graphic file with name cc-13-1798-g6.jpg — Figure 6. Cell senescence in Myc;LOX prostates. (A) Representative SA-βgal staining images in 3-mo-old prostates showing senescence in the Myc;LOX prostates. (B) Western blot analysis showing p27 expression in various prostate lobes of 3-mo mice among different genotypes. β-actin was used as the loading control. (C) Altered Rb1 and Phos-Rb in Myc;LOX prostates. Prostatic lobes were microdissected out from the animals of the indicated genotypes (3 mo) and used in western blotting analysis of the indicated molecules. (D) Increased Rb1cc1 mRNA expression in 15-LOX2 single or double transgenic prostates. Presented are the mean ± SD data from 2 sets of mice.