. Author manuscript; available in PMC: 2015 Jan 1.

Published in final edited form as: Genes Immun. 2014 May 1;15(5):275–281. doi: 10.1038/gene.2014.16

Table 2.

Summary of HyperLasso results from analyses of Box-Cox-transformed log₁₀ viral load in HIV-1 seroconverters.^a

SNP ID	Chr 6 position	Gene	Class	MAF	Allele	Haplotype block number^b	Relation to VL
1st analysis^c
rs1737004	29,869,190	HCG4\|HLA-G	upstream	0.439	C	93	Low
rs2394250	30,051,635	HCG9	ncRNA	0.282	T	NA	Low
rs3129813	30,446,226	RPP21\|HLA-E	intergenic	0.436	G	NA	High
rs404860	32,292,323	NOTCH4	intron	0.334	G	285	High
rs3819714	32,912,195	TAP2	intron	0.422	G	351	Low
2nd analysis^d
rs3094626	30,431,602	RPP21\|HLA-E	intergenic	0.430	C	133	Low
rs3134931	32,298,598	NOTCH4	intron	0.517	G	NA	High

Testing additive effects for the minor alleles (nucleotides) of single nucleotide polymorphism (SNPs); Chr, chromosome; MAF, minor allele frequency; VL, viral load

Not all eligible SNPs can be assigned to haplotype blocks (details are shown in Supplemental Materials). NA, not applicable.

First analysis has age and sex as covariates; overall R²=34.4% for the model.

Second analysis has age, sex, HLA-A*74, B*13 and B*57 as covariates; overall R²=28.9 for the model.