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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Genes Immun. 2014 May 1;15(5):275–281. doi: 10.1038/gene.2014.16

Table 3.

Summary of HyperLasso results from analysis of Box-Cox transformed log10 viral load (VL) in seroprevalent individuals.a

SNP ID Chr 6 position Gene Class MAF Allele Haplotype block
numberb
Relation to VL
1st Analysisc
  rs3823376 30,052,163 HCG9 ncRNA 0.404 G NA Low
  rs2517425 31,057,649 MUC21 intergenic 0.280 C 170 Low
  rs2857114 32,887,974 HLA-DQB2|HLA-DOB downstream 0.457 C 346 High
2nd analysisd
  rs2857114 32,887,974 HLA-DQB2|HLA-DOB downstream 0.457 C 346 High
a

Testing additive effects for the minor alleles of single nucleotide polymorphisms (SNPs); MAF, minor allele frequency.

b

Not all eligible SNPs can be assigned to haplotype blocks (details are shown in Supplemental Materials). NA, not applicable.

c

First analysis has adjusted for sex and age at VL measurement; overall R2=14.8% for the model.

d

Second analysis has adjusted for sex, age at VL measurement, HLA-A*36, A*74, B*57, B*81 and DRB1*01:02; Overall R2=14.9% for the model.