Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 May 7;96(2):239–246. doi: 10.1038/clpt.2014.77

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 American Society for Clinical Pharmacology and Therapeutics

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

PMC Copyright notice

Illustration of the components used to compute associations between drugs and medical conditions for signal detection using search logs. Each user is associated with a surveillance period (blue line) centered on the time of the user’s first query for a drug of interest (D). Associations are estimated by calculating the query rate ratio (QRR)—the ratio between the number of queries for a condition (C) or symptom (S) of interest outside the exclusion period (shaded region) after and before . In this example, QRR = (4 + 3 + 2)/(1 + 1 + 1) = 3.

Inline graphic — Illustration of the components used to compute associations between drugs and medical conditions for signal detection using search logs. Each user is associated with a surveillance period (blue line) centered on the time of the user’s first query for a drug of interest (D). Associations are estimated by calculating the query rate ratio (QRR)—the ratio between the number of queries for a condition (C) or symptom (S) of interest outside the exclusion period (shaded region) after and before . In this example, QRR = (4 + 3 + 2)/(1 + 1 + 1) = 3.