Table 4.
Variable | Heart rate | Systolic blood pressure | Diastolic blood pressure | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||||
beta | SE* | 95% CI ** | p | beta | SE* | 95% CI** | p | beta | SE* | 95% CI ** | p | |
CYP2D6 phenotype (PM) | 2.10 | 0.70 | 0.73,3.47 | 0.004 | − 0.03 | 1.6 | −3.17,3.11 | 0.97 | 0.50 | 0.7 | −2.8,3.8 | 0.50 |
Baseline heart rate (bpm) | − 0.34 | 0.04 | −0.42, −0.26 | < 0.0001 | ||||||||
Baseline SBP (mm Hg) | − 0.17 | 0.06 | −0.30, −0.05 | 0.003 | ||||||||
Baseline DBP (mm Hg) | − 0.21 | 0.07 | −0.35, −0.07 | 0.0026 | ||||||||
Age (years) | − 0.16 | 0.04 | −0.08, −0.24 | 0.0002 | 0.04 | 0.07 | −0.10,0.18 | 0.52 | − 0.01 | 0.04 | −0.09,0.07 | 0.74 |
Race (African American) | − 2.24 | 0.80 | −0.67, −3.8 | 0.007 | − 6.61 | 1.30 | −9.16, −4.06 | < 0.0001 | − 5.01 | 0.86 | −3.33, −7.70 | < 0.0001 |
Gender (Female) | 0.55 | 0.80 | −1.02,2.12 | 0.49 | 4.57 | 1.25 | 2.12,7.02 | 0.0003 | 3.48 | 0.82 | 1.88,5.36 | < 0.0001 |
SE: standard error,
CI: confidence interval