Table I.
Phase of disease | Sex | Age at diagnosis (years) | Time from diagnosis (months) | Baseline platelet count (n×109/L) | Overall response | Complete response | Relapse | Duration of response (days) | |
---|---|---|---|---|---|---|---|---|---|
1 | Newly diagnosed | F | 7 | 0.2 | 3 | No | X | X | X |
2 | Newly diagnosed | M | 12.7 | 0 | 5 | Yes | No | No | X |
3 | Newly diagnosed | M | 1.3 | 1.1 | 19 | Yes | No | Yes | 32 |
4 | Newly diagnosed | M | 11 | 1 | 17 | Yes | Yes | No | X |
5 | Newly diagnosed | F | 3.2 | 1 | 11 | Yes | No | Yes | 46 |
6 | Newly diagnosed | M | 5.8 | 2 | 3 | No | X | X | X |
7 | Newly diagnosed | F | 10.5 | 0 | 5 | Yes | Yes | No | X |
8 | Newly diagnosed | M | 10 | 2 | 8 | Yes | No | Yes | 28 |
9 | Newly diagnosed | M | 0.9 | 0 | 14 | No | X | X | X |
10 | Newly diagnosed | F | 15.4 | 1 | 4 | No | X | X | X |
11 | Newly diagnosed | F | 11 | 2 | 4 | Yes | No | Yes | 22 |
12 | Newly diagnosed | F | 12 | 2 | 6 | Yes | No | No | X |
13 | Persistent | M | 5.6 | 3 | 13 | Yes | Yes | Yes | 27 |
14 | Persistent | F | 14.6 | 4 | 6 | No | X | X | X |
15 | Persistent | F | 9 | 7 | 3 | Yes | No | Yes | 14.5 |
16 | Persistent | F | 9 | 6 | 14 | Yes | Yes | Yes | 41 |
17 | Persistent | M | 5 | 6 | 15 | Yes | No | Yes | 29 |
18 | Persistent | M | 12 | 8 | 5 | Yes | Yes | Yes | 13 |
19 | Persistent | F | 4 | 11 | 7 | Yes | Yes | Yes | 73 |
20 | Persitent | M | 1 | 5.7 | 2 | No | No | X | X |
21 | Chronic | F | 4.7 | 19 | 9 | Yes | Yes | Yes | 13 |
22 | Chronic | M | 5.8 | 26 | 4 | Yes | Yes | Yes | 77.37 |
23 | Chronic | M | 6.3 | 55 | 8 | Yes | Yes | Yes | 134 |
24 | Chronic | F | 10.5 | 21 | 8 | Yes | Yes | Yes | 65 |
25 | Chronic | F | 4.9 | 38 | 4 | No | X | X | X |
26 | Chronic | F | 8.9 | 27 | 19 | Yes | Yes | Yes | 89 |
27 | Chronic | M | 0.6 | 14 | 13 | Yes | No | Yes | 12 |
28 | Chronic | F | 1.5 | 137 | 22 | Yes | No | Yes | 19 |
29 | Chronic | M | 11 | 38 | 6 | Yes | No | Yes | 11 |
30 | Chronic | F | 2 | 36 | 0 | Yes | Yes | Yes | 20.6 |
31 | Chronic | F | 11 | 43 | 9 | Yes | Yes | Yes | 116 |
32 | Chronic | M | 7 | 19 | 7 | Yes | Yes | Yes | 34 |
33 | Chronic | F | 5 | 14 | 4 | No | No | X | 36.5 |
34 | Chronic | M | 12 | 48 | 7 | Yes | Yes | Yes | 111 |
Overall response: platelet count >50×109/L and at least 30×109/L over the baseline count and remission of active bleeding.
Complete response: platelet count >150×109/L.