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. 2013 Sep 12;98(11):4464–4474. doi: 10.1210/jc.2013-1069

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Copyright © 2013 by The Endocrine Society

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/us/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Acute changes in plasma kisspeptin levels in healthy women receiving twice-daily injections of saline or kisspeptin-54. A–C, Time profiles of plasma kisspeptin IR after sc bolus injection of saline or kisspeptin-54 (KP54) at time 0 on menstrual days 7 (A), 11 (B), and 14 (C) of the study protocol. D, Bar graph comparing mean preinjection kisspeptin IR after saline or kisspeptin-54 throughout the study protocol. All subjects commenced twice-daily treatment with saline or kisspeptin-54 on the morning of menstrual day 7 after their basal blood sample and finished treatment on the morning of day 14. Data are presented as mean ± SEM. *, P < .05; **, P < .01.