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. 2013 Sep 12;98(11):4464–4474. doi: 10.1210/jc.2013-1069

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Copyright © 2013 by The Endocrine Society

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/us/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Changes in LH pulsatility during the menstrual cycle of healthy women receiving twice-daily injections of saline or kisspeptin-54. All women underwent frequent blood sampling for 8 hours on menstrual days 6, 11, and 14 of the study protocol. Twice-daily sc bolus injections of saline or kisspeptin-54 (KP54) (6.4 nmol/kg) were self-administered between menstrual days 7 and 14. A and B, Mean values for secretory mass (A) and estimated pulses per 24 hours (B). C–E, Levels of pulsatile (C), basal (D), and total (E) LH secretion during each 8-h sampling study. Data are presented as mean ± SEM. *, P < .05; **, P < .01.