Table 1.

Breadth and depth of GO annotation of the Pichia pastoris genome^a

Biological process term name	GO ID	GOA
Autophagy	GO:0006914	26
Ascospore formation	GO:0030437	0
Carbohydrate metabolic process	GO:0005975	122
Cellular amino acid metabolic process	GO:0006520	184
Cell wall organisation or biogenesis	GO:0071554	7
Chromosome organisation	GO:0051276	48
Chromosome segregation	GO:0007059	9
Cofactor metabolic process	GO:0051186	74
Conjugation with cellular fusion	GO:0000747	1
Cytokinesis	GO:0000910	2
Cytoskeletal organisation	GO:0007010	31
DNA metabolic process	GO:0006259	132
Establishment or maintenance of cell polarity	GO:0007163	2
Generation of precursor metabolites and energy	GO:0006091	58
Iron sulfur cluster assembly	GO:0016226	7
Lipid metabolic process	GO:0006629	112
mRNA metabolic process	GO:0016071	28
Meiosis	GO:0007126	3
Mitochondrion organisation	GO:0007005	22
Nucleobase-containing metabolic process	GO:0055086	186
Nucleocytoplasmic transport	GO:0006913	9
Peroxisome organisation	GO:0007031	19
Protein catabolic process	GO:0030163	56
Protein complex assembly	GO:0006461	37
Protein folding	GO:0006457	40
Protein glycosylation	GO:0006486	22
Protein modification by protein conjugation	GO:0070647	14
Protein targeting	GO:0006605	37
Regulation of mitotic cell cycle	GO:0007346	4
Ribosome biogenesis	GO:0042254	43
Signalling	GO:0023052	116
tRNA metabolic process	GO:0006399	72
Transmembrane transport	GO:0055085	218
Translation	GO:0006412	227
Transcription, DNA-templated	GO:0006351	237
Vacuolar transport	GO:0007034	5
Vacuole organisation	GO:0007033	3
Vesicle-mediated transport	GO:0016192	78
Vitamin metabolic process	GO:0006766	19
No GO slim annotation		3177
Total number of genes		5040

^aP. pastoris GO annotation was from GOA version 125. Slimming was performed using the Generic GO Term Mapper (http://go.princeton.edu GO obo 10/01/2014)