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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Psychopharmacology (Berl). 2014 Feb 23;231(16):3179–3188. doi: 10.1007/s00213-014-3489-2

Fig. 3. Dissociating adenosine A1 receptor stimulation from extinction training has no effect on extinction responding or subsequent reinstatement.

Fig. 3

(a) Average number of cocaine infusions and active lever responses in each 4 h session over the last 5 days of the self-administration phase. (b) Systemic treatment with the A1AR agonist, CPA (0.1 mg/kg, ip), 4 h after each extinction session has no effect on extinction responding. A1AR stimulation temporally dissociated from extinction training has no effect on (c) cue-, (d) cocaine or (e) D2 agonist-induced reinstatement.