Table 4.
Meta-Analytic Connectivity Modelling (MACM) Results for the Subgenual Cingulum Cluster Using Standard or Modified Algorithm
Standard MACM |
Modified MACM |
|||
---|---|---|---|---|
Cluster (Number of Voxels) / Brain Region (Histological Assignmenta) |
x y z | z-score | x y z | z-score |
Cluster 1 (kS = 2632 / kM = 2531) | ||||
L/R subgenual cingulate cortex (Area s32) | −4 36 −10 | 8.57 | −4 36 −10 | 8.35 |
L/R perigenual cingulate cortex (Area p24) | 2 38 0 | 8.33 | 2 38 0 | 8.23 |
L perigenual cingulate cortex / frontal pole (Area p32, Fp2) b |
−4 56 −10 | 5.06 | −4 56 −10 | 8.16 |
R subgenual cingulate cortex (Area s24) | 8 16 −12 | 4.67 | 8 16 −12 | 8.16 |
L Ncl. Accumbens / Ventral Pallidum | −8 4 −8 | 4.61 | −8 4 −10 | 8.16 |
R Ncl. Accumbens | 10 10 −10 | 3.96 | - | - |
L subgenual cingulate cortex (Area 25, 33) | −2 10 −6 | 3.90 | −2 10 −6 | 8.15 |
Cluster 2 (kS = 535 / kM = 484) | ||||
L dorsal posterior cingulate cortex | −6 −52 24 | 7.04 | −6 −52 24 | 8.18 |
L ventral posterior cingulate cortex | −4 −50 14 | 4.04 | −6 52 14 | 8.15 |
R dorsal posterior cingulate cortex | 8 −52 30 | 3.70 | 8 −54 30 | 8.15 |
Cluster 3 (kS = 272 / kM = 108) | ||||
L hippocampus (CA2, CA3) | −22 −14 −20 | 5.71 | −22 −14 −20 | 8.17 |
L amygdala (LB, SF) | −20 −8 −22 | 4.97 | −20 −8 −22 | 8.16 |
Cluster 4 (kS = 119 / kM = 72) | ||||
L inferior parietal lobule (PGp, PGa) | −48 −66 32 | 4.30 | −48 −66 32 | 8.16 |
Cluster 5 (kM = 250) | ||||
R anterior ITG | - | - | 50 −2 −34 | 8.14 |
Cluster 6 (kM = 70) | ||||
L anterior ITG | - | - | −54 −12 −26 | 8.15 |
Cluster 7 (kM = 69) | ||||
R medial temporal pole | - | - | 30 14 −34 | 8.15 |
Cluster 8 (kM = 69) | ||||
R medial cerebellum | - | - | 10 −62 −40 | 8.15 |
Cluster 9 (kM = 66) | ||||
L medial cerebellum | - | - | −8 −52 −44 | 8.14 |
Cluster 10 (kM = 51) | ||||
R superior frontal gyrus | - | - | 20 32 48 | 8.15 |
Notes. x, y, z = peak voxel coordinates in MNI space; kS/kM = number of voxels in cluster obtained with standard/modified MACM algorithm.
References for cytoarchitectonically defined areas: Amunts et al. 2005; Bludau et al. 2013; Caspers et al. 2006; Palomero-Gallagher et al. 2009.
Forming a separate cluster with modified MACM: kM = 221.
L = left; R = right; Ncl. = nucleus; ITG = inferior temporal gyrus.