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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: DNA Repair (Amst). 2014 Feb 20;20:23–31. doi: 10.1016/j.dnarep.2014.01.007

Figure 4. Crystal structure of Fpg WT Phe114 wedge residue and Fpg F114A variant interrogating damaged and undamaged guanosine DNA bases.

Figure 4

Residue 114 is colored red, while the interrogated base is colored purple. (A) Phe114 interaction with guanosine-containing DNA (2F5O). (B) Phe114 interaction with 8-oxoG containing DNA (1R2Y). (C) Ala114 interaction with guanosine-containing DNA (4G4Q). (D) Ala114 interaction with 8-oxoG-containing DNA (4G4R).