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(A) A diagram showing the arrangement of guanines in a G-quartet. Polymorphism of HTG in the presence of sodium and potassium ions (B) a Basket-type conformation in the presence of Na+ (PDB: 143D) (C) a Propellar-type conformation in the presence of K+ with parallel strand topology (PDB: 3SC8), and (D) a Hybrid (3 + 1)-type conformation with three parallel and one antiparallel strands (PDB: 2GKU).
