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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Trends Endocrinol Metab. 2014 Mar 26;25(8):399–406. doi: 10.1016/j.tem.2014.02.005

Figure 4. Modelling [Ca2+]i upon glucose gradient.

Figure 4

Map of [Ca2+]i elevation upon a gradient of glucose metabolism, with [Ca2+]i time courses from indicated cells. Time courses are offset for clarity, with vertical bar indicating change of 0.1μM. Small amount of excitation bleed through is circled which is experimentally measured. Otherwise, a sharp transition between an area of coordinated excitability and quiescent behavior can be seen. Figure adapted from [54].