Figure 5.

Biodistribution of amyloid detection peptide p5R radiolabeled with ¹²⁵I. Animals (n=9 per group pooled from 2 separate experiments) were injected with clodronate liposomes at day −1 (white bars), day +1 (gray bars) or no clodronate injected (black bars) relative to AEF injection at day 0. At 2 weeks post-AEF, mice were injected with ¹²⁵I-p5R and euthanized 2 h later. Data are shown as % injected dose/gram of wet tissue ± SD bars. There were no significant differences in biodistribution (ANOVA analyses) among the 3 groups for liver or spleen.