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. Author manuscript; available in PMC: 2014 Jul 27.
Published in final edited form as: Amyloid. 2014 Jan 22;21(1):45–53. doi: 10.3109/13506129.2013.876400

Table 1.

Analyses of AA amyloid in huIL-6 mice as a function of time post AEF treatment*

Post AEF
(wk)		 Congo red
(0–4+)		 p5 (%ID/g)
Liver Spleen Liver Spleen
0 0 0 0.83±0.23 0.70±0.15
2 0.59±0.33 1.02±0.57 1.9±0.52 3.7±1.74
3 1.75±0.83 2.62±0.65 6.13±3.0 10.2±1.8
4 2.5±0.93 3.25±0.83 7.7±2.7 12.7±1.6
5 3.0±0 4.0±0 10.6±2.9 13.2±2.9
*

huIL-6 mice were treated with 10 μg of AEF (iv) for the designated time and then sacrificed 2 h post injection of 125I P5 peptide. Liver and spleen sections were scored for Congo red stain (0–4+) and tissues analyzed for accumulation of p5 (% injected dose/gram of wet tissue) ± SD. N= 4 mice per group.