Table 2.
15 min post injection | |||||
---|---|---|---|---|---|
Spleen | Liver | ||||
Clodronate + | Control | t-test | Clodronate + | Control | t-test |
8.3 ± 3.1 | 6.4 ± 0.6 | p = 0.51 | 17.8 ± 3.5 | 19.5 ± 1.4 | p = 0.48 |
4 h post injection | |||||
Spleen | Liver | ||||
Clodronate + | Control | t-test | Clodronate + | Control | t-test |
18.1 ± 11.5 | 2.4 ± 0.5 | p = 0.014 | 11.4 ± 2.9 | 6.3 ± 1.1 | p = 0.006 |
huIL6 mice, either clodronate treated or controls (day −1), were injected with 125I AEF (see Figure 3) and at the designated times, animals (n=3/group for 15 min and N=5/group for 4 h) were euthanized and analyzed for % injected dose/gram of wet tissue of 125I content ± standard deviation.