Figure 6. ESCRT-I dynamics during early zygotic development.
Individual images of GFP:MVB-12 illustrate its distribution at various times relative to zygote ovulation. Long arrows highlight GFP:MVB-12 accumulation on early endosomes near the plasma membrane during the second wave of clathrin-mediated endocytosis (+23 min timepoint). Short arrowheads highlight the localization of ESCRT-I to midbodies. Inset is a 3x zoomed view of the area highlighted by an arrow. Scale bar, 20 μm. Inset scale bar, 5 μm.