Figure 8.

PEM/PVA microfilms promote normal wound healing in excisional splinted wounds in mice. Figures (a, b, c) show gross images of wounds on post-operative days 0, 7 and 14, respectively, that were modified post-surgery with silver/PEMs (with silver loading of 16.8 ± 0.5 μg cm⁻²). Each line on the scale represents 1 mm. (d) Percentage of original wound size on post-operative days 3, 5, 7, 10 and 14 in wounds that did not receive PEMs and wounds that were modified with either PEMs containing no silver or PEMs containing 16.8 ± 0.5 μg cm⁻² silver. There were no significant difference on wound sizes between the three experimental groups. Each data point presents mean ± SEM of relative wound size. The sample size (n) for days 3, 5, and 7 were n = 8, 16 and 16, respectively, for each group. On day 7, some wounds were harvested for histopathology. The sample sizes for the three groups on days 10 and 14 were n = 4, 6 and 6, respectively