Table 3.

Medication Possession Ratios and Respiratory Morbidities

Odds ratios are calculated for a 10% increase in MPR (Adherence)		Odds Ratio [95% C.I.]*	P value	Total number of responses (n=28 participants)†
Acute Care Use	Emergency Department	0.75 [0.58, 0.97]	0.03	72
	Hospitalization	0.71 [0.47, 1.06]	0.10	74
	Steroid use	0.99 [0.84, 1.16]	0.88	73
	Antibiotic use	1.01 [0.88, 1.17]	0.85	74
Symptomatic Outcomes	Days with trouble breathing	1.12 [0.92, 1.36]	0.25	70
	Rescue medication use	0.84 [0.73, 0.98]	0.03	70
	Activity limitations	0.71 [0.53, 0.95]	0.02	70
	Caregiver awake at night	0.78 [0.53, 1.14]	0.20	70

^*Logistic regressions clustered by participant (GEE Methodology) and adjusted for age in years at the time of visit and disease severity (gestational age and the use of oxygen as recorded at the first clinic visit).

^†Participants (n=28) had a mean (±SD) of 2.6 ± 1.7 responses at separate clinic visits. Out of 33 individuals in the Prescription Claims Sample, 5 individuals did not complete questionnaires covering these outcomes.