. Author manuscript; available in PMC: 2014 Jul 28.

Published in final edited form as: Biol Blood Marrow Transplant. 2009 Aug 3;15(10):1265–1270. doi: 10.1016/j.bbmt.2009.06.001

Table 2.

Grading of Cardiac Complications after allo-HSCT*

Cardiac Complication	Grade
Cardiac Complication	1	2	3	4	5
Arrhythmia	Asymptomatic, intervention not indicated	Nonurgent medical intervention indicated	Incompletely controlled, medically or with device (eg, pacemaker)	Life-threatening (eg, associated with CHF, hypotension, syncope, shock	Death
Congestive Heart Failure	Asymptomatic diagnostic finding; intervention not indicated	Asymptomatic, intervention indicated	Symptomatic CHF responsive to intervention	Refractory CHF, poorly controlled; intervention such as ventricular assist device or heart transplant indicated	Death
Cardiac Ischemia	Asymptomatic arterial narrowing without ischemia	Asymptomatic and testing suggesting ischemia; stable angina	Symptomatic; testing consistent with ischemia; unstable angina; intervention needed	Acute myocardial infarction	Death

CHF indicates congestive heart failure; allo-HSCT, allogeneic hematopoietic stem cell transplantation.

Adapted from Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0 (CTCAE v3.0), DCTD, NCI, NIH, DHHS.