Skip to main content
. Author manuscript; available in PMC: 2014 Jul 28.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Aug 3;15(10):1265–1270. doi: 10.1016/j.bbmt.2009.06.001

Table 3.

Impact of Prognostic factors on Outcome

N NRM at Day 100
P-Value Risk of Cardiac Complications
95% CI P- Value
HR 95% CI HR
Age
 ≤43 28 Ref. Ref.
 >43 28 2.6 0.5–13.4 0.25 2.9 0.6–15.2 .2
HCT-CI
 1–2 39 Ref
 >2 17 0.9 0.2–4.5 0.9 0.3 0.04–2.8 0.3
Donor type
 Matched related 23 0.2 0.02–1.4 0.1 0.5
 Matched unrelated 23 Ref. Ref. 0.8
 Mismatched 10 0.4 0.05–3.8 0.5 can’t estimate
Pre-TP LVEF
 ≤35 10 Ref. Ref.
 36–40 21 1.6 0.2–15.1 0.7 1.6 0.2–16 0.7
 >40 25 1.3 0.1–13 0.8 1.3 0.1–12.5 0.8
Smoking status
 Smoker 20 0.7 0.1–3.4 0.6 3.9 0.7–20.2 0.1
 Nonsmoker 36 Ref.
Prep regimen
 Ablative 21 0.7 0.1–3.4 0.6 0.2 0.03–2.0 0.2
 Reduced intensity 35 Ref.
Cyclophosphamide in prep regimen
 Yes 17 0.9 0.2–4.7 0.9 1.6 0.3–6.9 0.6
 No 39 Ref.
Diagnosis
 Acute leukemia 32 Ref. Ref.
 Lymphoma 16 1.5 0.2–8.8 0.7 1.4 0.2–8.4 0.7
 Others 8 3 0.5–17.9 0.2 3.5 0.5–18.3

NRM indicates nonrelapse mortality; HR, hazard ratio; CI, confidence interval; HCT-CI, hematopoietic stem cell transplantation comorbidity index; TP, transplant; Prep regimen, preparative regimen.