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. Author manuscript; available in PMC: 2015 Jan 24.
Published in final edited form as: Nature. 2014 Jul 22;511(7510):421–427. doi: 10.1038/nature13595

Figure 1. Manhattan plot.

Figure 1

Manhattan plot of the discovery genome-wide association meta-analysis of 49 case control samples (34,241 cases and 45,604 controls) and 3 family based association studies (1,235 parent affected-offspring trios). The x-axis is chromosomal position and the y-axis is the significance of association (−log10(P)).The red line shows the genome-wide significance level (5×10−8). SNPs in green are in LD with the index SNPs (diamonds) which represent independent genome-wide significant associations.