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. 2014 Jul 14;87(1040):20140080. doi: 10.1259/bjr.20140080

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© 2014 The Authors. Published by the British Institute of Radiology

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Figure 3. — Cancers classified as Breast Imaging Reporting and Data System (BI-RADS) 3, 4 or 5 in digital mammography (DM) and classified as BI-RADS 1 or 2 in digital breast tomosynthesis (DBT) by at least two readers, most likely because of interpretative error. (a) A case of a 59-year-old female with a cluster of microcalcifications in DBT and DM, classified as BI-RADS 3, 4 or 5 by four readers in DM and classified as BI-RADS 1 or 2 by two readers in DBT. Histology showed a 45 × 25-mm ductal carcinoma in situ, grade 3. (b) A case of a 63-year-old female with a spiculated lesion in DBT and DM, classified as BI-RADS 3, 4 or 5 by all readers in DM and classified as BI-RADS 1 or 2 by two readers in DBT. The lesion was deemed to be less conspicuous in DBT than in DM, but still clearly visible. Microscopy revealed a 10-mm invasive tubular carcinoma, grade 1. (c) A case of a 66-year-old female with a spiculated, retromamillary lesion in DBT and DM craniocaudal (CC) view, classified as BI-RADS 3, 4 or 5 by all readers in DM and classified as BI-RADS 1 or 2 by two readers in DBT. Microscopy revealed a 10-mm invasive ductal carcinoma, grade 2. (d) A case of a 50-year-old female with architectural distortion in DBT and DM mediolateral oblique view, but without any findings in the CC view, classified as BI-RADS 1 or 2 by three readers in both DBT and DM. Histology showed a large multicentric invasive lobular carcinoma within two areas (90 × 40 mm and 10 × 5 mm). MLO, mediolateral oblique.