Table 1.
Baseline Characteristics of the Study Population by Primary End Point (Cardiac Death) Within 5 Years After Ischemic Stroke
| Overall | Cardiac Death | No Cardiac Death | P | |
|---|---|---|---|---|
| No. of participants, N/n | 655 | 44 | 611 | |
| Demographics | ||||
| Age, mean (SD), y | 69.7 (12.7) | 75.06 (11.7) | 69.33 (12.65) | 0.0037 |
| Male, No. (%) | 292 (44.58) | 26 (59.09) | 266 (43.54) | 0.045 |
| Race/ethnicity | 0.5039 | |||
| Non-Hispanic white, No. (%) | 124 (18.9) | 11 (25) | 113 (18.49) | |
| Non-Hispanic black, No. (%) | 181 (27.6) | 10 (22.73) | 171 (27.99) | |
| Hispanic, No. (%) | 336 (51.3) | 23 (52.27) | 313 (51.23) | |
| Other race, No. (%) | 14 (2.1) | … | 14 (2.29) | |
| Risk of factors, No. (%) | ||||
| History of MI (n = 654) | 106 (16.2) | 14 (31.82) | 92 (15.08) | 0.0036 |
| History of CAD | 219 (33.4) | 25 (56.82) | 194 (31.75) | 0.0007 |
| Current smoking (n = 652) | 132 (21.3) | 8 (26.67) | 124 (30.86) | NS |
| Diabetes mellitus (n = 654) | 295 (45.1) | 19 (43.18) | 276 (45.17) | 0.7978 |
| Hypertension | 546 (83.36) | 37 (84.09) | 509 (83.31) | 0.8926 |
| Hypercholesterolemia (n = 655) | 280 (435) | 17 (38.64) | 268 (43.86) | 0.4995 |
| Stroke etiologic subtypes, No. (%) | ||||
| Atherosclerotic, external | 48 (7.33) | 3 (6.82) | 45 (7.36) | 0.8931 |
| Atherosclerotic, internal | 52 (7.94) | 3 (6.82) | 49 (8.02) | 0.7759 |
| Lacunar | 152 (23.2) | 3 (6.82) | 149 (24.39) | 0.0077 |
| Cardioembolic | 127 (19.4) | 19 (43.18) | 108 (17.68) | <0.0001 |
| Cryptogenic | 256 (39.08) | 13 (29.55) | 243 (39.77) | 0.1794 |
| Stroke severity (n = 620) | 0.0009* | |||
| NIHSS 0–5 | 318 (51.29) | 15 (36.59) | 303 (52.33) | |
| NIHSS 6–13 | 200 (32.26) | 10 (24.29) | 190 (32.82) | |
| NIHSS ≥14 | 102 (16.45) | 16 (39.02) | 86 (14.85) | |
All percentages calculated with n = 655, unless noted otherwise.
*
Cochran-Armitage test for trend (2-sided).
NS indicates nonsignificant.