Table 4.

Multivariate Model of Predictors of 5-Year Risk of Cardiac Death or MI After First Ischemic Stroke

Variable	Clinical Diagnosis			Neuroimaging Diagnosis
	HR	95% CI Limits		HR	95% CI Limits
Left parietal location	3.30	1.45	7.51	3.49	1.38	8.80
Right parietal location	1.90	0.68	5.32	3.13	1.04	9.45
Frontal location	0.84	0.39	1.80	0.93	0.41	2.09
Left temporal location	2.26	0.85	6.00	2.69	0.96	7.53
Right temporal location	2.49	0.81	7.68	1.84	0.51	6.58
Lacunar location*	0.74	0.32	1.75	0.64	0.23	1.75
Age	1.03	1.01	1.06	1.04	1.02	1.07
Male sex	1.68	0.96	2.95	2.18	1.13	4.19
CAD	2.33	1.35	4.02	2.79	1.51	5.15
NIHSS 6–13	1.04	0.54	2.00	0.75	0.35	1.61
NIHSS ≥14	1.79	0.81	3.93	2.13	0.80	5.67
Medium size†	…	…	…	0.44	0.16	1.23
Large size†	…	…	…	0.53	0.15	1.86

^*Lacunar stroke compared with other stroke subtypes (large-vessel external/internal, embolic, cryptogenic, large-vessel).

^†Size of stroke: small (less than half of lobe), medium (half of lobe to 1 lobe), and large (>1 lobe). Adapted from National Institute of Neurological Disorders and Stroke report.²⁸