The antibiotics used are depicted in colored rectangles, with beta-lactams in blue (cephalexin, cefepime, and piperacillin–tazobactam), clindamycin in green, glycopeptides in pink (vancomycin and teicoplanin), and daptomycin in yellow; the number in each rectangle corresponds to the number of days of treatment with the antibiotic. The drugs are shown in the order in which they were added to therapy. Dosages were as follows: cephalexin, 500 mg every 6 hours, given orally; clindamycin, 450 mg every 8 hours, given orally; cefepime, 1 g every 8 hours, given intravenously; piperacillin–tazobactam, 3.375 g every 6 hours, given intravenously; vancomycin, 1 g every 12 hours, given intravenously; teicoplanin, 400 mg daily, given intravenously; and daptomycin, 6 mg per kilogram of total body weight daily, given intravenously. The final days of hospitalization are not included. SSTI denotes skin and soft-tissue infection, BR-VSSA vancomycin-susceptible S. aureus, BR-VRSA vancomycin-resistant S. aureus, and VREF vancomycin-resistant Enterococcus faecalis.