Table 2.

Association between characteristics of female sex hormones and cardiovascular disease outcomes in 600 women with rheumatoid arthritis (RA).

Characteristic	Coronary Heart Disease	Heart Failure	Cerebrovascular disease	Peripheral Vascular disease	General cardiovascular disease (incl CHD, HF, cerebrovascular disease & PVD)
Early Menopause	1.42 (0.85, 2.39)	1.14 (0.69, 1.87)	1.41 (0.76, 2.62)	0.51 (0.16, 1.64)	1.55 (1.07, 2.23)
Artificial menopause	0.71 (0.33, 1.53)	0.82 (0.40, 1.69)	1.19 (0.54, 2.60)	0.24 (0.03, 1.74)	0.80 (0.46, 1.39)
Any pregnancy/birth	1.01 (0.65, 1.58)	0.92 (0.62, 1.36)	0.68 (0.41, 1.13)	0.92 (0.46, 1.82)	0.96 (0.68, 1.33)
Any HRT exposure	1.02 (0.68, 1.53)	0.72 (0.48, 1.07)	1.26 (0.77, 2.07)	0.84 (0.41, 1.72)	1.05 (0.77, 1.43)

^*Values in the table are hazard ratio (95% confidence interval). All models adjusted for age (as the time-scale) and calendar year of RA

CHD = coronary heart disease, HF = heart failure, PVD = peripheral vascular disease