Table 1.

Details of group break, downexperimental treatments and summary of results. Gonadectomy (GDx) was performed 7 days prior to infusions and behavioral trials. Systemic E₂ treatment was provided via subcutaneous slow-release pellet inserted at time of GDx, or locally via bilateral infusion into the main olfactory bulbs.

Experimental Groups
Experiment 1
Experimental Group	1A	1B	1C	1D	1E
Sex	Female	Female	Male	Male	Male
Surgical Tx	GDx	GDx	GDx	GDx	Sham
Systemic Drug	E2	None	E2	None	None
Local Bulbar Infusion	None	None	None	None	None
Odor memory duration	> 30 min	< 30 min	> 30 min	< 30 min	< 30 min

Experiment 2
Experimental Group	2A		2B
Sex	Female		Female
Surgical Tx	GDx + Cannulation		GDx + Cannulation
Systemic Drug	E2		None
Local Bulbar Infusion	Saline	PHTPP	Saline
Odor memory duration	> 30 min	< 30 min	< 30 min

Experiment 3
Experimental Group	3A			3B
Sex	Female			Male
Surgical Tx	GDx + Cannulation			GDx + Cannulation
Systemic Drug	None			None
Local Bulbar Infusion	Saline	E2	PHTPP+E2	Saline	E2	PHTPP+E2
Odor memory duration	< 30 min	> 30 min	< 30 min	< 30 min	> 30 min	< 30 min